Article
Three-dimensional reconstruction of the intercalated disc including the intercellular junctions by applying volume scanning electron microscopy.
Histochemistry and cell biology - 1 May 2018
Vanslembrouck Bieke, Kremer Anna, Pavie Benjamin, van Roy Frans, Lippens Saskia, van Hengel Jolanda
Abstract excerpt
The intercalated disc (ID) contains different kinds of intercellular junctions: gap junctions (GJs), desmosomes and areae compositae, essential for adhesion and communication between adjacent cardiomyocytes. The junctions can be identified based on their morphology when imaged using transmission electron microscopy (TEM), however, only with very limited information in the z-dimension. The application of volume EM...
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