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Article

Phenotype-driven identification of epithelial signalling clusters.

Scientific reports - 5 Mar 2018

Marques Elsa, Peltola Tomi, Kaski Samuel, Klefström Juha

Abstract excerpt

In metazoans, epithelial architecture provides a context that dynamically modulates most if not all epithelial cell responses to intrinsic and extrinsic signals, including growth or survival signalling and transforming oncogene action. Three-dimensional (3D) epithelial culture systems provide tractable models to interrogate the function of human genetic determinants in establishment of context-dependency. We...

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Identifiers

PMID: 29507319
DOI: 10.1038/s41598-018-22293-x
PMCID: PMC5838230

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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