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Article

Quantitative Phenotypic Image Analysis of Three-Dimensional Organotypic Cultures.

Methods in molecular biology (Clifton, N.J.) - 1 Jan 2017

Åkerfelt Malin, Toriseva Mervi, Nees Matthias

Abstract excerpt

Glandular epithelial cells differentiate into three-dimensional (3D) multicellular or acinar structures, particularly when embedded in laminin-rich extracellular matrix (ECM). The spectrum of different multicellular morphologies formed in 3D is a reliable indicator for the differentiation potential of normal, non-transformed cells compared to different stages of malignant progression. Motile cancer cells may...

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PMID: 28634961
DOI: 10.1007/978-1-4939-7021-6_31

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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