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Article

Slow Adaptive Response of Budding Yeast Cells to Stable Conditions of Continuous Culture Can Occur without Genome Modifications.

Genes - 27 Nov 2020

Klim Joanna, Zielenkiewicz Urszula, Kurlandzka Anna, Kaczanowski Szymon, Skoneczny Marek

Abstract excerpt

Continuous cultures assure the invariability of environmental conditions and the metabolic state of cultured microorganisms, whereas batch-cultured cells undergo constant changes in nutrients availability. For that reason, continuous culture is sometimes employed in the whole transcriptome, whole proteome, or whole metabolome studies. However, the typical method for establishing uniform growth of a cell...

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PMID: 33261040
DOI: 10.3390/genes11121419
PMCID: PMC7759791

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