Article
Investigation of the association between Toll-like receptor 2 gene polymorphisms and Behçet's disease in Japanese patients.
Human immunology - 1 Jan 2009
Tomiyama Ryuichi, Meguro Akira, Ota Masao, Katsuyama Yoshihiko, Nishide Tadayuki, Uemoto Riyo, Iijima Yasuhito, Ohno Shigeaki, Inoko Hidetoshi, Mizuki Nobuhisa
Abstract excerpt
Behçet's disease (BD) is a chronic systemic inflammatory disorder characterized by recurrent ocular symptoms, oral and genital ulcers, and skin lesions. The etiology of BD is still uncertain, but genetic and environmental factors likely both play an important role in BD development. In the present study, we investigated whether polymorphisms of Toll-like receptor 2 (TLR2), previously reported to recognize BD...
Topics
- Asian People
- Behcet Syndrome
- Genetic Predisposition to Disease
- Humans
- Polymorphism, Single Nucleotide
- Toll-Like Receptor 2