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Article

Association of NOD1, NOD2, PYDC1 and PYDC2 genes with Behcet's disease susceptibility and clinical manifestations.

Ophthalmic genetics - 1 Dec 2021

Kocaaga Ayca, Cakmak Genc Gunes, Karakas Celık Sevim, Koca Rafet, Dursun Ahmet

Abstract excerpt

Purpose: Behçet's disease (BD) is an autoinflammatory disease with clinical manifestations such as mucocutaneous, ocular, vascular, gastrointestinal, musculoskeletal and central nervous system involvement. Features of innate and adaptive immunity and inflammasome pathways have been claimed in the pathogenesis of BD. We aimed to investigate the roles of NOD1, NOD2, PYDC1 and PYDC2 genes in the genetic...

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PMID: 34294014
DOI: 10.1080/13816810.2021.1955273

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