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Article

Contribution of MTHFR gene variants in lupus related subclinical atherosclerosis.

Clinical immunology (Orlando, Fla.) - 1 Aug 2018

Giannelou Maira, Nezos Andrianos, Fragkioudaki Sofia, Kasara Dimitra, Maselou Kyriaki, Drakoulis Nikolaos, Ioakeimidis Dimitris, Moutsopoulos Haralampos M, Mavragani Clio P

Abstract excerpt

OBJECTIVE: Elevated concentrations of homocysteine have been previously identified as an independent risk factor for subclinical atherosclerosis in patients with systemic lupus erythematosus (SLE). Given that heightened homocysteine levels are known to be strongly influenced by genetic factors, in the current study we investigated the contribution of high homocysteine levels as well as of functional polymorphisms...

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Source

Identifiers

PMID: 29501539
DOI: 10.1016/j.clim.2018.02.014

Genes

MTHFR

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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