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Article

MTHFR polymorphisms (rs1801133) and systemic lupus erythematosus risk: A meta-analysis.

Medicine - 2 Oct 2020

Zhou Huang-Yan, Yuan Min

Abstract excerpt

BACKGROUND: The relationship between MTHFR (5, 10-methylene tetrahydrofolate reductase) gene polymorphisms and Systemic Lupus Erythematosus (SLE) has been wildly studied, but the results are still conflicting. Therefore, the purpose of this meta and pooled analysis was to identify the role of the MTHFR SNP (single nucleotide polymorphism, rs1801133) in SLE in a large sample of subjects and to assess the risk of...

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PMID: 33019481
DOI: 10.1097/MD.0000000000022614
PMCID: PMC7535654

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