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Article

A1298C polymorphism in the MTHFR gene predisposes to cardiovascular risk in rheumatoid arthritis.

Arthritis research & therapy - 1 Jan 2010

Palomino-Morales Rogelio, Gonzalez-Juanatey Carlos, Vazquez-Rodriguez Tomas R, Rodriguez Luis, Miranda-Filloy Jose A, Fernandez-Gutierrez Benjamin, Llorca Javier, Martin Javier, Gonzalez-Gay Miguel A

Abstract excerpt

INTRODUCTION: We determined the contribution of the methylene tetrahydrofolate reductase (MTHFR) 677 C>T and 1298 A>C gene polymorphisms to the susceptibility to rheumatoid arthritis (RA). We also assessed whether these two MTHFR gene polymorphisms may be implicated in the development of cardiovascular (CV) events and subclinical atherosclerosis manifested by the presence of endothelial dysfunction, in a series...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Methylenetetrahydrofolate Reductase (NADPH2)

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Source

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Identifiers

PMID: 20423475
DOI: 10.1186/ar2989
PMCID: PMC2888227

Genes

MTHFR

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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