Article
Homocysteine, methylenetetrahydrofolate reductase polymorphism, antiphospholipid antibodies, and thromboembolic events in systemic lupus erythematosus: a retrospective cohort study.
The Journal of rheumatology - 1 Sept 1998
Fijnheer R, Roest M, Haas F J, De Groot P G, Derksen R H
Abstract excerpt
OBJECTIVE: To examine the relationship between plasma homocysteine, 5,10-methylenetetrahydrofolate reductase (MTHFR) polymorphism, and the risk of arterial and/or venous thrombosis in systemic lupus erythematosus (SLE). METHODS: Plasma homocysteine and MTHFR polymorphism were determined in a retr...
Topics
- Adolescent
- Adult
- Aged
- Antibodies, Antiphospholipid
- Cohort Studies
- Female
- Genotype
- Heart Diseases
- Homocysteine
- Humans
- Lupus Erythematosus, Systemic
- Male
- Methylenetetrahydrofolate Reductase (NADPH2)
- Middle Aged
- Oxidoreductases Acting on CH-NH Group Donors
- Polymorphism, Genetic
- Retrospective Studies
- Thromboembolism