Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Change in Populations of Macrophages Promotes Development of Delayed Gastric Emptying in Mice.

Gastroenterology - 1 Jun 2018

Cipriani Gianluca, Gibbons Simon J, Miller Katie E, Yang Daniel S, Terhaar Matthew L, Eisenman Seth T, Ördög Tamas, Linden David R, Gajdos Gabriela B, Szurszewski Joseph H, Farrugia Gianrico

Abstract excerpt

BACKGROUND & AIMS: Muscularis propria macrophages lie close to cells that regulate gastrointestinal motor function, including interstitial cells of Cajal (ICC) and myenteric neurons. In animal models of diabetic gastroparesis, development of delayed gastric emptying has been associated with loss of macrophages that express cytoprotective markers and reduced networks of ICC. Mice with long-term diabetes and normal...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Diabetes Mellitus, Experimental
Share to Immunohistochemistry

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Macrophage Colony-Stimulating Factor

Share to Macrophages

Share to Muscle, Smooth

Share to Stomach

Share to Streptozocin

Source

Open in PubMed Open full text

Identifiers

PMID: 29501441
DOI: 10.1053/j.gastro.2018.02.027
PMCID: PMC5985210

Genes

CSF1
TNF

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Change in Populations of Macrophages Promotes Development of Delayed Gastric Emptying in Mice.PMID 29501441Read ↗

Age-dependent shift in macrophage polarisation causes inflammation-mediated degeneration of enteric nervous system.Semantic proximity Read ↗

Dedicated macrophages organize and maintain the enteric nervous system.Semantic proximity Read ↗

Intestinal neuron-associated macrophages in health and diseaseSemantic proximity Read ↗

Minireview: Emerging Concepts in Islet Macrophage Biology in Type 2 DiabetesSemantic proximity Read ↗

Accumulation of M1-like macrophages in type 2 diabetic islets is followed by a systemic shift in macrophage polarization.Semantic proximity Read ↗

Macrophage-associated pro-inflammatory state in human islets from obese individualsSemantic proximity Read ↗

Inhibition of Notch activity suppresses hyperglycemia-augmented polarization of macrophages to the M1 phenotype and alleviates acute pancreatitis.Semantic proximity Read ↗

Human and mouse regenerative macrophages enhance beta cell survival, function, and proliferationSemantic proximity Read ↗

Zebrafish harbor diverse intestinal macrophage populations including a subset intimately associated with enteric neural processesSemantic proximity Read ↗

A model to study the phenotypic changes of interstitial cells of Cajal in gastrointestinal diseases.Semantic proximity Read ↗

Differential gene expression in functional classes of interstitial cells of Cajal in murine small intestineSemantic proximity Read ↗

Macrophages in the murine pancreas and their involvement in fetal endocrine development in vitro.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.