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Article

A model to study the phenotypic changes of interstitial cells of Cajal in gastrointestinal diseases.

Gastroenterology - 1 Mar 2010

Ro Seungil, Park Chanjae, Jin Jingling, Zheng Huili, Blair Peter J, Redelman Doug, Ward Sean M, Yan Wei, Sanders Kenton M

Abstract excerpt

BACKGROUND & AIMS: Interstitial cells of Cajal (ICC) express the receptor tyrosine kinase, KIT, the receptor for stem cell factor. In the gastrointestinal (GI) tract, ICC are pacemaker cells that generate spontaneous electrical slow waves, and mediate inputs from motor neurons. Absence or loss of...

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Source

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Identifiers

PMID: 19917283
DOI: 10.1053/j.gastro.2009.11.007
PMCID: PMC4793910

Genes

KIT

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-19917283-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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