Article
Macrophages in the murine pancreas and their involvement in fetal endocrine development in vitro.
Journal of leukocyte biology - 1 Oct 2005
Geutskens S B, Otonkoski T, Pulkkinen M-A, Drexhage H A, Leenen P J M
Abstract excerpt
Macrophages are a heterogeneous population of cells that belong to the mononuclear phagocyte system. They play an important role in tissue homeostasis and remodeling and are also potent immune regulators. Pancreatic macrophages are critically involved in the development and pathogenesis of autoimmune diabetes. To elucidate the ontogeny of pancreatic macrophages, we characterized in this study the macrophages...
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