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Article

Elevated serum RANTES chemokine levels in autoimmune Addison disease.

Polish archives of internal medicine - 30 Apr 2018

Fichna Marta, Żurawek Magdalena, Budny Bartłomiej, Komarowska Hanna, Niechciał Elżbieta, Fichna Piotr, Ruchała Marek

Abstract excerpt

INTRODUCTION Regulated on activation, normal T‑cell expressed and secreted chemokine (RANTES), the product of the CCL5 gene, is involved in trafficking immune cells into the inflammation site. It acts as coactivator of T cells and promotes polarization of the immune response towards the Th1 profile. In autoimmune Addison disease (AAD), the adrenal cortex is gradually destroyed by adrenal‑specific immune cell...

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PMID: 29498364
DOI: 10.20452/pamw.4221

Genes

CCL5

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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