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Article

Potential Transcriptional Biomarkers to Guide Glucocorticoid Replacement in Autoimmune Addison’s Disease

4 Jan 2021

Abstract excerpt

Abstract Background No reliable biomarkers exist to guide glucocorticoid (GC) replacement treatment in autoimmune Addison’s disease (AAD), leading to overtreatment with alarming and persistent side effects or undertreatment, which could be fatal. Objective To explore changes in gene expression following different GC replacement doses as a means of identifying candidate transcriptional biomarkers to guide GC...

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Share to Adrenal Hormones and Disorders
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PMID: 33553982
DOI: 10.1210/jendso/bvaa202

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