Article
Peripheral Blood Cells from Patients with Autoimmune Addison's Disease Poorly Respond to Interferons In Vitro, Despite Elevated Serum Levels of Interferon-Inducible Chemokines.
Journal of interferon & cytokine research : the official journal of the International Society for Interferon and Cytokine Research - 1 Oct 2015
Edvardsen Kine, Bjånesøy Trine, Hellesen Alexander, Breivik Lars, Bakke Marit, Husebye Eystein S, Bratland Eirik
Abstract excerpt
Autoimmune Addison's disease (AAD) is a disorder caused by an immunological attack on the adrenal cortex. The interferon (IFN)-inducible chemokine CXCL10 is elevated in serum of AAD patients, suggesting a peripheral IFN signature. However, CXCL10 can also be induced in adrenocortical cells stimul...
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