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Article

Role of the X-linked gene GPR174 in autoimmune Addison's disease.

The Journal of clinical endocrinology and metabolism - 1 Jan 2015

Napier C, Mitchell A L, Gan E, Wilson I, Pearce S H S

Abstract excerpt

CONTEXT: Autoimmune endocrinopathies demonstrate a profound gender bias, but the reasons for this remain obscure. The 1000 genes on the X chromosome are likely to be implicated in this inherent susceptibility; various theories, including skewed X chromosome inactivation and fetal microchimerism, have been proposed. GPR174 is an Xq21 putative purinergic receptor that is widely expressed in lymphoid tissues. A...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Share to Polymorphism, Single Nucleotide

Share to Receptors, G-Protein-Coupled

Source

Identifiers

PMID: 25295623
DOI: 10.1210/jc.2014-2694

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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