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Article

CTLA-4 as a genetic determinant in autoimmune Addison's disease.

Genes and immunity - 1 Sept 2015

Wolff A S B, Mitchell A L, Cordell H J, Short A, Skinningsrud B, Ollier W, Badenhoop K, Meyer G, Falorni A, Kampe O, Undlien D, Pearce S H S, Husebye E S

Abstract excerpt

In common with several other autoimmune diseases, autoimmune Addison's disease (AAD) is thought to be caused by a combination of deleterious susceptibility polymorphisms in several genes, together with undefined environmental factors and stochastic events. To date, the strongest genomic association with AAD has been with alleles at the HLA locus, DR3-DQ2 and DR4. The contribution of other genetic variants has...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 26204230
DOI: 10.1038/gene.2015.27
PMCID: PMC4561510

Genes

CD28
ICOS

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

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CTLA-4 as a genetic determinant in autoimmune Addison's disease.PMID 26204230Read ↗

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