Article
TNF promoter polymorphisms are associated with genetic susceptibility in COPD secondary to tobacco smoking and biomass burning.
International journal of chronic obstructive pulmonary disease - 1 Jan 2018
Reséndiz-Hernández Juan Manuel, Ambrocio-Ortiz Enrique, Pérez-Rubio Gloria, López-Flores Luis Alberto, Abarca-Rojano Edgar, Pavón-Romero Gandhi Fernando, Flores-Trujillo Fernando, de Jesús Hernández-Zenteno Rafael, Camarena Ángel, Pérez-Rodríguez Martha, Salazar Ana María, Ramírez-Venegas Alejandra, Falfán-Valencia Ramcés
Abstract excerpt
Background: Smoking and smoke from biomass burning (BB) are the main environmental risk factors for COPD. Clinical differences have been described between COPD related to smoking and related to wood smoke, but no studies have shown genetic differences between patients exposed to these two risk factors. Methods: To investigate a possible association of tumor necrosis factor (TNF) promoter polymorphisms, we...
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