Article
Genetic variants in IL17A and serum levels of IL-17A are associated with COPD related to tobacco smoking and biomass burning.
Scientific reports - 21 Jan 2020
Ponce-Gallegos Marco A, Pérez-Rubio Gloria, Ambrocio-Ortiz Enrique, Partida-Zavala Neftali, Hernández-Zenteno Rafael, Flores-Trujillo Fernando, García-Gómez Leonor, Hernández-Pérez Andrea, Ramírez-Venegas Alejandra, Falfán-Valencia Ramcés
Abstract excerpt
IL-17A is an important pro-inflammatory cytokine involved in the inflammatory response in chronic obstructive pulmonary disease (COPD). To evaluate the role played by single nucleotide polymorphisms of IL17A and protein levels in susceptibility to COPD, 1,807 subjects were included in a case-control study; 436 had COPD related to tobacco smoking (COPD-S) and 190 had COPD related to biomass burning (COPD-BB). Six...
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