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Article

Heritable DNA methylation marks associated with susceptibility to breast cancer.

Nature communications - 28 Feb 2018

Joo Jihoon E, Dowty James G, Milne Roger L, Wong Ee Ming, Dugué Pierre-Antoine, English Dallas, Hopper John L, Goldgar David E, Giles Graham G, Southey Melissa C

Abstract excerpt

Mendelian-like inheritance of germline DNA methylation in cancer susceptibility genes has been previously reported. We aimed to scan the genome for heritable methylation marks associated with breast cancer susceptibility by studying 25 Australian multiple-case breast cancer families. Here we report genome-wide DNA methylation measured in 210 peripheral blood DNA samples provided by family members using the...

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Identifiers

PMID: 29491469
DOI: 10.1038/s41467-018-03058-6
PMCID: PMC5830448

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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