Article
[Genotypic resistance to sulfamide drugs among patients with Pneumocystis jiroveci pneumonia].
Medicina clinica - 1 May 2004
Calderón Enrique, de la Horra Carmen, Montes-Cano Marco Antonio, Respaldiza Nieves, Martín-Juan José, Varela José Manuel
Abstract excerpt
BACKGROUND AND OBJECTIVE: The absence of culture methods to recognize the presence of resistance to sulfa or sulfone drugs in Pneumocystis jiroveci has led to develop molecular techniques based on the identification of mutations in the dihydropteroate synthase gene (DHPS). The aim of this study was to determine the frequency of these mutations in our geographical area, since in Spain there is no information...
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