Article
Gene-based evaluation of low-frequency variation and genetically-predicted gene expression impacting risk of keloid formation.
Annals of human genetics - 1 Jul 2018
Hellwege Jacklyn N, Russell Shirley B, Williams Scott M, Edwards Todd L, Velez Edwards Digna R
Abstract excerpt
Keloids are benign dermal tumors occurring approximately 20 times more often in individuals of African descent as compared to individuals of European descent. While most keloids occur sporadically, a genetic predisposition is supported by both familial aggregation of some keloids and large differences in risk among populations. Despite Africans and African Americans being at increased risk over lighter-skinned...
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