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Aberrant connective tissue differentiation towards cartilage and bone underlies human keloids in African Americans

11 Dec 2016

Abstract excerpt

Keloids are benign fibroproliferative tumors more frequently found among African Americans. Until now, keloid etiopathogenesis is not fully understood. To characterize keloids in African Americans, we performed transcriptional profiling of biopsies from large chronic keloids, adjacent non-lesional (NL) skin (n=3) and a newly formed keloid lesion using Affymetrix HGU133 2.0 plus arrays. Quantitative RT-PCR...

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PMID: 27943413
DOI: 10.1111/exd.13271

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