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Article

Admixture mapping identifies a locus at 15q21.2-22.3 associated with keloid formation in African Americans.

Human genetics - 1 Dec 2014

Velez Edwards Digna R, Tsosie Krystal S, Williams Scott M, Edwards Todd L, Russell Shirley B

Abstract excerpt

Keloids are benign dermal tumors that occur ~20 times more often in African versus Caucasian descent individuals. While most keloids occur sporadically, a genetic predisposition is supported by both familial aggregation of some keloids and the large differences in risk among populations. Yet, no well-established genetic risk factors for keloids have been identified. In this study, we conducted admixture mapping...

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Identifiers

PMID: 25280642
DOI: 10.1007/s00439-014-1490-9
PMCID: PMC4334317

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NEDD4

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