Article
A genome-wide association study identifies four susceptibility loci for keloid in the Japanese population.
Nature genetics - 1 Sept 2010
Nakashima Mitsuko, Chung Suyoun, Takahashi Atsushi, Kamatani Naoyuki, Kawaguchi Takahisa, Tsunoda Tatsuhiko, Hosono Naoya, Kubo Michiaki, Nakamura Yusuke, Zembutsu Hitoshi
Abstract excerpt
Keloid is a dermal fibroproliferative growth that results from dysfunction of the wound healing processes. Through a multistage genome-wide association study using 824 individuals with keloid (cases) and 3,205 unaffected controls in the Japanese population, we identified significant associations of keloid with four SNP loci in three chromosomal regions: 1q41, 3q22.3-23 and 15q21.3. The most significant...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.