Article
Comprehensive integrative analyses identify GLT8D1 and CSNK2B as schizophrenia risk genes.
Nature communications - 26 Feb 2018
Yang Cui-Ping, Li Xiaoyan, Wu Yong, Shen Qiushuo, Zeng Yong, Xiong Qiuxia, Wei Mengping, Chen Chunhui, Liu Jiewei, Huo Yongxia, Li Kaiqin, Xue Gui, Yao Yong-Gang, Zhang Chen, Li Ming, Chen Yongbin, Luo Xiong-Jian
Abstract excerpt
Recent genome-wide association studies (GWAS) have identified multiple risk loci that show strong associations with schizophrenia. However, pinpointing the potential causal genes at the reported loci remains a major challenge. Here we identify candidate causal genes for schizophrenia using an integrative genomic approach. Sherlock integrative analysis shows that ALMS1, GLT8D1, and CSNK2B are schizophrenia risk...
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