Article
GWAS meta analysis identifies TSNARE1 as a novel Schizophrenia / Bipolar susceptibility locus.
Scientific reports - 29 Oct 2013
Sleiman Patrick, Wang Dai, Glessner Joseph, Hadley Dexter, Gur Raquel E, Cohen Nadine, Li Qingqin, Hakonarson Hakon
Abstract excerpt
We carried out a GWAS meta-analysis of combined mixed-ancestry schizophrenia, schizoaffective, and bipolar cohorts that resulted in the identification of six genome-wide significant loci, including one novel locus at chr8q24.3, encompassing TSNARE1 (P = 1.28 × 10(-9)). The analysis included a total of 13,394 cases and 34,676 controls. While the function of TSNARE1 remains unknown, bioinformatic predictions based...
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