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Article

Methods for fine-mapping with chromatin and expression data.

PLoS genetics - 1 Feb 2018

Roytman Megan, Kichaev Gleb, Gusev Alexander, Pasaniuc Bogdan

Abstract excerpt

Recent studies have identified thousands of regions in the genome associated with chromatin modifications, which may in turn be affecting gene expression. Existing works have used heuristic methods to investigate the relationships between genome, epigenome, and gene expression, but, to our knowledge, none have explicitly modeled the chain of causality whereby genetic variants impact chromatin, which impacts gene...

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PMID: 29481575
DOI: 10.1371/journal.pgen.1007240
PMCID: PMC5843356

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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