Cancer evolution, mutations, and clonal selection in relapse neuroblastoma.

Abstract excerpt

The notion of cancer as a complex evolutionary system has been validated by in-depth molecular analyses of tumor progression over the last years. While a complex interplay of cell-autonomous programs and cell-cell interactions determines proliferation and differentiation during normal development, intrinsic and acquired plasticity of cancer cells allow for evasion of growth factor limitations, apoptotic signals,...

Topics

Share this publication in a Topic to start or enrich a Post.

• Share to Clone Cells
• Share to Immunotherapy
• Share to Mutation