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Article

Antidepressant treatment effects on dopamine transporter availability in patients with major depression: a prospective 123I-FP-CIT SPECT imaging genetic study.

Journal of neural transmission (Vienna, Austria : 1996) - 1 Jun 2018

Hellwig Sabine, Frings Lars, Masuch Annette, Vach Werner, Domschke Katharina, Normann Claus, Meyer Philipp T

Abstract excerpt

We investigated if sleep deprivation (SD) and electroconvulsive therapy (ECT) affect striatal dopamine transporter (DAT) availability assessed by single-photon emission computed tomography (SPECT) and 123I-FP-CIT, if dopamine transporter gene (SLC6A3; DAT) variation modifies aforementioned parameters, and if SD response or SD-induced DAT changes correlate with ECT response. Sixteen patients with major depression...

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PMID: 29476250
DOI: 10.1007/s00702-018-1863-7

Genes

CIT

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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