Article
Effects of C825T polymorphism of the GNB3 gene on availability of dopamine transporter in healthy volunteers--a SPECT study.
NeuroImage - 1 Jun 2011
Chen Po See, Yeh Tzung Lieh, Lee I Hui, Lin Cheng Bill, Tsai Hsin Chun, Chen Kao Chin, Chiu Nan-Tsing, Yao Wei Jen, Yang Yen Kuang, Chou Yuan-Hwa
Abstract excerpt
Striatal dopaminergic activity is significantly correlated with various cognitive activities, mood regulation, and even metabolic homeostasis, and is modulated by the dopamine transporter (DAT). The availability of DAT could be regulated by presynaptic autoreceptors, which are G-protein coupled receptors; however, whether functional variations in the common downstream signaling molecule, G-protein, could cause...
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