Article
Uncommon Human Telomerase Reverse Transcriptase Promoter Mutations Are Associated With Poor Survival in Ovarian Clear Cell Carcinoma.
American journal of clinical pathology - 7 Mar 2018
Nishikimi Kyoko, Nakagawa Kiyoshi, Tate Shinichi, Matsuoka Ayumu, Iwamoto Masami, Kiyokawa Takako, Shozu Makio
Abstract excerpt
OBJECTIVES: The present study assessed whether human telomerase reverse transcriptase (TERT) promoter mutations mediate the increased mortality risk observed in patients with ovarian clear cell carcinoma (CCC) and characterized the pathologic features of TERT promoter mutation-associated ovarian CCC. METHODS: The TERT promoter region in genomic DNA extracted from paraffin-embedded ovarian CCC specimens (n = 93)...
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