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Article

PNPLA3 Association with Alcoholic Liver Disease in a Cohort of Heavy Drinkers.

Alcohol and alcoholism (Oxford, Oxfordshire) - 1 Jul 2018

Kolla Bhanu Prakash, Schneekloth Terry D, Biernacka Joanna, Shah Vijay, Lazaridis Konstantinos N, Geske Jennifer, Karpyak Victor

Abstract excerpt

AIMS: Prior studies have established variation at the PNPLA3 gene to be associated with a risk of developing alcoholic liver disease (ALD). We attempt to replicate this finding and other potential genetic variations previously associated with ALD utilizing a case-control design in a cohort of subjects with alcohol use disorders. SHORT SUMMARY: This case-control study performed in a US clinical sample of heavy...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Open in PubMed Open full text

Identifiers

PMID: 29474507
DOI: 10.1093/alcalc/agy007
PMCID: PMC6016697

Genes

PNPLA3
AQP2
NVL

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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