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Article

Role of candidate gene variants in modulating the risk and severity of alcoholic hepatitis.

Alcoholism, clinical and experimental research - 1 Apr 2021

Beaudoin James J, Liang Tiebing, Tang Qing, Banini Bubu A, Shah Vijay H, Sanyal Arun J, Chalasani Naga P, Gawrieh Samer

Abstract excerpt

BACKGROUND: Alcoholic hepatitis (AH) is a severe and life-threatening alcohol-associated liver disease. Only a minority of heavy drinkers acquires AH and severity varies among affected individuals, suggesting a genetic basis for the susceptibility to and severity of AH. METHODS: A cohort consisting of 211 patients with AH and 176 heavy drinking controls was genotyped for five variants in five candidate genes that...

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PMID: 33616244
DOI: 10.1111/acer.14581
PMCID: PMC8076096

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Source receipt: pubmed, retrieved 7 Sept 2026.

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