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Article

The Heterogeneity Between Lynch-Associated and Sporadic MMR Deficiency in Colorectal Cancers.

Journal of the National Cancer Institute - 1 Sept 2018

Liu Guo-Chen, Liu Ran-Yi, Yan Jun-Ping, An Xin, Jiang Wu, Ling Yi-Hong, Chen Jie-Wei, Bei Jin-Xin, Zuo Xiao-Yu, Cai Mu-Yan, Liu Ze-Xian, Zuo Zhi-Xiang, Liu Ji-Hong, Pan Zhi-Zhong, Ding Pei-Rong

Abstract excerpt

Background: Previous studies demonstrated that prognosis of germline deficiency in mismatch repair protein (dMMR) was different from that of sporadic dMMR. The underlying mechanism has not been studied. Methods: From a prospectively maintained database, we collected dMMR colorectal cancer (CRC) patients identified by postoperative immunohistochemistry screening. According to genetic test, patients were grouped as...

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Identifiers

PMID: 29471527
DOI: 10.1093/jnci/djy004

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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