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Article

The GyrA-box determines the geometry of DNA bound to gyrase and couples DNA binding to the nucleotide cycle.

Nucleic acids research - 1 Nov 2012

Lanz Martin A, Klostermeier Dagmar

Abstract excerpt

DNA gyrase catalyses the adenosine triphosphate-dependent introduction of negative supercoils into DNA. The enzyme binds a DNA-segment at the so-called DNA-gate and cleaves both DNA strands. DNA extending from the DNA-gate is bound at the perimeter of the cylindrical C-terminal domains (CTDs) of the GyrA subunit. The CTDs are believed to contribute to the wrapping of DNA around gyrase in a positive node as a...

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Identifiers

PMID: 22977179
DOI: 10.1093/nar/gks852
PMCID: PMC3510516

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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