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Article

A residue of motif III positions the helicase domains of motor subunit HsdR in restriction-modification enzyme EcoR124I.

Journal of molecular modeling - 26 Jun 2018

Sinha Dhiraj, Bialevich Vitali, Shamayeva Katsiaryna, Guzanova Alena, Sisakova Alexandra, Csefalvay Eva, Reha David, Krejci Lumir, Carey Jannette, Weiserova Marie, Ettrich Rüdiger

Abstract excerpt

Type I restriction-modification enzymes differ significantly from the type II enzymes commonly used as molecular biology reagents. On hemi-methylated DNAs type I enzymes like the EcoR124I restriction-modification complex act as conventional adenine methylases at their specific target sequences, but unmethylated targets induce them to translocate thousands of base pairs through the stationary enzyme before...

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PMID: 29943199
DOI: 10.1007/s00894-018-3722-8

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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A residue of motif III positions the helicase domains of motor subunit HsdR in restriction-modification enzyme EcoR124I.PMID 29943199Read ↗

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