Article
GWAS identifies two novel colorectal cancer loci at 16q24.1 and 20q13.12.
Carcinogenesis - 3 May 2018
Tanikawa Chizu, Kamatani Yoichiro, Takahashi Atsushi, Momozawa Yukihide, Leveque Karine, Nagayama Satoshi, Mimori Koshi, Mori Masaki, Ishii Hideshi, Inazawa Johji, Yasuda Jun, Tsuboi Akito, Shimizu Atsushi, Sasaki Makoto, Yamaji Taiki, Sawada Norie, Iwasaki Motoki, Tsugane Shoichiro, Naito Mariko, Wakai Kenji, Koyama Teruhide, Takezaki Toshiro, Yuji Koichiro, Murakami Yoshinori, Nakamura Yusuke, Kubo Michiaki, Matsuda Koichi
Abstract excerpt
Colorectal cancer (CRC) is the fourth leading cause of cancer mortality worldwide. Genome-wide association studies (GWAS) identified more than 50 CRC loci. However, most of the previous studies were conducted in European population, and host genetic factors among Japanese population are largely remained to be identified. To identify novel loci in the Japanese population, here, we performed a large-scale GWAS...
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