The SNP rs961253 in 20p12.3 is associated with colorectal cancer risk: a case-control study and a meta-analysis of the published literature.

doi:10.1371/journal.pone.0034625

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Article

The SNP rs961253 in 20p12.3 is associated with colorectal cancer risk: a case-control study and a meta-analysis of the published literature.

PloS one - 1 Jan 2012

Zheng Xiawen, Wang Li, Zhu Yaowu, Guan Qing, Li Huijun, Xiong Zhigang, Deng Lingyan, Lu Jie, Miao Xiaoping, Cheng Liming

Abstract excerpt

BACKGROUND: Colorectal cancer (CRC) is the third common cancer and the fourth leading cause of cancer death worldwide. A single nucleotide polymorphism (SNP), rs961253 located in 20p12, was firstly described to be associated with the increased risk of CRC in a genome-wide association study; however, more recent replication studies yielded controversial results. METHODOLOGY/PRINCIPAL FINDINGS: A hospital-based...

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PMID: 22509336
DOI: 10.1371/journal.pone.0034625
PMCID: PMC3324501

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