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Article

Impact of clinical factors and UGT1A9 and CYP2B6 genotype on inter-individual differences in propofol pharmacokinetics.

Journal of anesthesia - 1 Apr 2018

Kanaya Akihiro, Sato Toshihiro, Fuse Nobuo, Yamaguchi Hiroaki, Mano Nariyasu, Yamauchi Masanori

Abstract excerpt

PURPOSE: Propofol is one of the most widely used fast-acting intravenously administered anesthetics. However, although large inter-individual differences in dose requirements and recovery time have been observed, there are few previous studies in which the association between several potential covariates, including genetic factors such as the UGT1A9 and CYP2B6 genotypes, and propofol pharmacokinetics was...

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Identifiers

PMID: 29468507
DOI: 10.1007/s00540-018-2470-3

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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