Article
The MYO6 interactome reveals adaptor complexes coordinating early endosome and cytoskeletal dynamics.
EMBO reports - 1 Apr 2018
O'Loughlin Thomas, Masters Thomas A, Buss Folma
Abstract excerpt
The intracellular functions of myosin motors requires a number of adaptor molecules, which control cargo attachment, but also fine-tune motor activity in time and space. These motor-adaptor-cargo interactions are often weak, transient or highly regulated. To overcome these problems, we use a proximity labelling-based proteomics strategy to map the interactome of the unique minus end-directed actin motor MYO6....
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.