Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Drug addiction and stress-response genetic variability: association study in African Americans.

Annals of human genetics - 1 Jul 2014

Levran Orna, Randesi Matthew, Li Yi, Rotrosen John, Ott Jurg, Adelson Miriam, Kreek Mary Jeanne

Abstract excerpt

Stress is a significant risk factor in the development of drug addictions and in addiction relapse susceptibility. This hypothesis-driven study was designed to determine if specific SNPs in genes related to stress response are associated with heroin and/or cocaine addiction in African Americans. The analysis included 27 genes (124 SNPs) and was performed independently for each addiction. The sample consisted of...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Black or African American
Share to Case-Control Studies

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Computational Biology

Share to Genetic Association Studies

Share to Polymorphism, Single Nucleotide

Share to Stress, Physiological

Share to Stress, Psychological

Share to Substance-Related Disorders

Source

Open in PubMed Open full text

Identifiers

PMID: 24766650
DOI: 10.1111/ahg.12064
PMCID: PMC4065216

Genes

GALR1
AVP
CRHBP
FKBP5
OXTR

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 3 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Drug addiction and stress-response genetic variability: association study in African Americans.PMID 24766650Read ↗

Stress-related genes and heroin addiction: a role for a functional FKBP5 haplotype.Semantic proximity Read ↗

Further evidence for the association of GAL, GALR1 and NPY1R variants with opioid dependence.Semantic proximity Read ↗

Heroin addiction in African Americans: a hypothesis-driven association study.Semantic proximity Read ↗

Opiate addiction and cocaine addiction: underlying molecular neurobiology and genetics.Semantic proximity Read ↗

Genetic variations in genes of the stress response pathway are associated with prolonged abstinence from heroin.Semantic proximity Read ↗

The genetics of the opioid system and specific drug addictions.Semantic proximity Read ↗

A non-coding CRHR2 SNP rs255105, a cis-eQTL for a downstream lincRNA AC005154.6, is associated with heroin addiction.Semantic proximity Read ↗

High Genetic Addiction Risk Score (GARS) in Chronically Prescribed Severe Chronic Opioid Probands Attending Multi-pain Clinics: an Open Clinical Pilot Trial.Semantic proximity Read ↗

Multi-variant Genetic Panel for Genetic Risk of Opioid Addiction.Semantic proximity Read ↗

Association of a polymorphism in the Homer1 gene with cocaine dependence in an African American population.Semantic proximity Read ↗

Pro-opiomelanocortin gene variation related to alcohol or drug dependence: evidence and replications across family- and population-based studies.Semantic proximity Read ↗

Genetic association of GABA-A receptor alpha-2 and mu opioid receptor with cocaine cue-reactivity: evidence for inhibitory synaptic neurotransmission involvement in cocaine dependence.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.