Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Restoration of conformation of mutant p53.

Annals of oncology : official journal of the European Society for Medical Oncology - 1 May 2018

Green J A, Von Euler M, Abrahmsen L B

Abstract excerpt

No abstract is available from the source.

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Alkylation
Share to Aminoquinolines
Share to Antineoplastic Agents
Share to Clinical Trials as Topic

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Protein Interaction Domains and Motifs

Share to Pyrazoles

Share to Pyrroles

Share to Structure-Activity Relationship

Source

Identifiers

PMID: 29462239
DOI: 10.1093/annonc/mdy057

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 23 Oct 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Restoration of conformation of mutant p53.PMID 29462239Read ↗

Pharmacological rescue of mutant p53 conformation and function.Semantic proximity Read ↗

Reactivation of mutant p53: molecular mechanisms and therapeutic potential.Semantic proximity Read ↗

Structural studies on mechanisms to activate mutant p53.Semantic proximity Read ↗

New insights into p53 function from structural studies.Semantic proximity Read ↗

Wild-type p53 adopts a 'mutant'-like conformation when bound to DNA.Semantic proximity Read ↗

Pseudo-mutant p53 as a targetable phenotype of <i>DNMT3A</i> -mutated pre-leukemiaSemantic proximity Read ↗

Re-engineered p53 chimera with enhanced homo-oligomerization that maintains tumor suppressor activity.Semantic proximity Read ↗

Phosphomimetic Mutation Destabilizes the Central Core Domain of Human p53.Semantic proximity Read ↗

Conformational shifts propagate from the oligomerization domain of p53 to its tetrameric DNA binding domain and restore DNA binding to select p53 mutants.Semantic proximity Read ↗

Covalent Rescue of Mutant p53Semantic proximity Read ↗

Structure and functionality of a designed p53 dimer.Semantic proximity Read ↗

Pseudo-mutant P53 is a unique phenotype of DNMT3A-mutated pre-leukemia.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.