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Article

Polymorphisms of CYP27B1 are associated with IFN efficacy in HBeAg-positive patients.

Journal of clinical laboratory analysis - 1 Jun 2018

Wu Yingying, Zeng Yongbin, Wu Wennan, Lin Jinpiao, Ou Qishui

Abstract excerpt

BACKGROUND: Host single nucleotide polymorphisms were associated with antiviral therapy in CHB patients. The CYP27B1 gene, encoding 25(OH)D3 -1α hydroxylase, might activate 25(OH)D3 to 1,25(OH)2 D3 in kidney resulted in influencing the efficacy of interferon (IFN). The aim of the study was to investigate the association between CYP27B1 polymorphisms and the response to IFN in HBeAg-positive patients. METHODS:...

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Share to 25-Hydroxyvitamin D3 1-alpha-Hydroxylase
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Hepatitis B, Chronic

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Source

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Identifiers

PMID: 29457277
DOI: 10.1002/jcla.22367
PMCID: PMC6817160

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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