Article
Association of vitamin-D-related genetic variations and treatment response to pegylated interferon in patients with chronic hepatitis B.
Antiviral therapy - 1 Jan 2017
Limothai Umaporn, Chuaypen Natthaya, Khlaiphuengsin Apichaya, Chittmittraprap Salyavit, Poovorawan Yong, Tangkijvanich Pisit
Abstract excerpt
BACKGROUND: Vitamin D, a potent immune-modulator, has been linked to the pathogenesis of chronic hepatitis B (CHB). This study was aimed at investigating the association between single nucleotide polymorphisms (SNPs) in vitamin-D-related genes and treatment response to pegylated interferon (PEG-IFN) in patients with CHB. METHODS: A total of 275 Thai patients (122 hepatitis B e antigen [HBeAg]-positive and 153...
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