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Article

Differential expression of the TWEAK receptor Fn14 in IDH1 wild-type and mutant gliomas.

Journal of neuro-oncology - 1 Jun 2018

Hersh David S, Peng Sen, Dancy Jimena G, Galisteo Rebeca, Eschbacher Jennifer M, Castellani Rudy J, Heath Jonathan E, Legesse Teklu, Kim Anthony J, Woodworth Graeme F, Tran Nhan L, Winkles Jeffrey A

Abstract excerpt

The TNF receptor superfamily member Fn14 is overexpressed by many solid tumor types, including glioblastoma (GBM), the most common and lethal form of adult brain cancer. GBM is notable for a highly infiltrative growth pattern and several groups have reported that high Fn14 expression levels can increase tumor cell invasiveness. We reported previously that the mesenchymal and proneural GBM transcriptomic subtypes...

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Source

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Identifiers

PMID: 29453678
DOI: 10.1007/s11060-018-2799-3
PMCID: PMC6047063

Genes

IDH1
TNF

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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