Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Glioma IL13Rα2 Is Associated with Mesenchymal Signature Gene Expression and Poor Patient Prognosis

18 Oct 2013

Abstract excerpt

A major challenge for successful immunotherapy against glioma is the identification and characterization of validated targets. We have taken a bioinformatics approach towards understanding the biological context of IL-13 receptor α2 (IL13Rα2) expression in brain tumors, and its functional significance for patient survival. Querying multiple gene expression databases, we show that IL13Rα2 expression increases with...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cancer-related molecular mechanisms research
Share to Circular RNAs in diseases
Share to Glioma Diagnosis and Treatment

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 24204956
DOI: 10.1371/journal.pone.0077769

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Glioma IL13Rα2 Is Associated with Mesenchymal Signature Gene Expression and Poor Patient PrognosisPMID 24204956Read ↗

Interleukin-13 receptor alpha 2 cooperates with EGFRvIII signaling to promote glioblastoma multiforme.Semantic proximity Read ↗

Stem-like Tumor-Initiating Cells Isolated from IL13Rα2 Expressing Gliomas Are Targeted and Killed by IL13-Zetakine–Redirected T CellsSemantic proximity Read ↗

IL-13 receptors as possible therapeutic targets in diffuse intrinsic pontine gliomaSemantic proximity Read ↗

Distinct tumor-TAM interactions in IDH-stratified glioma microenvironments unveiled by single-cell and spatial transcriptomicsSemantic proximity Read ↗

Transcriptional regulatory networks of tumor-associated macrophages that drive malignancy in mesenchymal glioblastoma.Semantic proximity Read ↗

Glioportal: a comprehensive transcriptomic resource unveiling ligand-mediated mesenchymal transition in glioblastomaSemantic proximity Read ↗

Molecular subtypes and prognostic analysis of cytokine-related genes in gliomasSemantic proximity Read ↗

PI3K signaling promotes inflammatory tumor-macrophage crosstalk associated with mesenchymal glioblastomaSemantic proximity Read ↗

Oncostatin-M differentially regulates mesenchymal and proneural signature genes in gliomas via STAT3 signaling.Semantic proximity Read ↗

Tumor-associated monocytes promote mesenchymal transformation through EGFR signaling in gliomaSemantic proximity Read ↗

IL8 associated with M2 macrophage infiltration as a prognostic biomarker differentiates WHO grade III and grade IV gliomasSemantic proximity Read ↗

Characterization and Functional Analysis of scFv-based Chimeric Antigen Receptors to Redirect T Cells to IL13Rα2-positive GliomaSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.