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Article

Insights into an Ancient Atypical Kinase Essential for Biosynthesis of Coenzyme Q.

Cell chemical biology - 15 Feb 2018

Clarke Catherine F

Abstract excerpt

COQ8 proteins are homologs of atypical protein kinases required for the biosynthesis of coenzyme Q (CoQ). In this issue of Cell Chemical Biology, Reidenbach et al. (2018) show that COQ8 has an ATPase activity, required for CoQ biosynthesis, that is strongly activated by cardiolipin and small molecule mimics of early CoQ intermediates.

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PMID: 29452608
DOI: 10.1016/j.chembiol.2018.02.001

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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