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Article

[Uveal melanoma, a model disease for splicing alterations and oncogenesis].

Medecine sciences : M/S - 1 Feb 2018

Alsafadi Samar, Mobuchon Lenha, Rodrigues Manuel, Stern Marc-Henri

Abstract excerpt

Uveal melanoma is a rare cancer in adults, whose highly stereotyped oncogenic events have been decrypted over the last decade. Its epidemiological, genetic and transcriptional features make it a remarkable model of oncogenesis. Malignant transformation involves almost mutually exclusive alteration of fundamental biologic pathways, including chromatin regulation with inactivation of BAP1, splicing with mutations...

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Share to Cell Proliferation
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 29451486
DOI: 10.1051/medsci/20183402013

Genes

BAP1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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